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Vetsulin (Insulin) 40 units/ml, 10 ml

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Vetsulin® (porcine insulin zinc suspension) is approved by the FDA to reduce hyperglycemia and associated clinical signs in pets with diabetes mellitus.

What is Vetsulin?

Vetsulin is an ideal insulin choice for your canine and feline patients with diabetes. It is an FDA-approved prescription insulin manufactured by Merck Animal Health that is used to reduce hyperglycemia and hyperglycemia-associated clinical signs.

Who is Vetsulin for?

For use in cats and dogs.

Why use Vetsulin?

Vetsulin® is the only insulin approved by the FDA for use in diabetic pets in the United States.

How does Vetsulin work?

  • Porcine insulin has a similar amino acid structure to canine insulin. It is considered an intermediate acting insulin.
  • Vetsulin® has two activity peaks after administration in dogs - one around 4 hours and another around 11. Activity duration varies, but is typically 14 to 24 hours.
  • In cats, the activity peak occurs between 1.5 and 8 hours, and activity duration varies at 8 to 12 hours.
  • Peak activity, activity duration, and required dose to adequately control diabetic symptoms will all vary between patients.


Merck Animal Health

Active ingredient(s):

Vetsulin® is a sterile aqueous zinc suspension of purified porcine insulin.

How is Vetsulin sold?

Vetsulin® is supplied as a sterile injectable suspension in multidose vials containing either 2.5 mL or 10 mL of 40 IU/mL porcine insulin zinc suspension. Vials are supplied in cartons of one 10 mL vial and cartons of ten 2.5 mL vials.

What are the side effects of Vetsulin?
While rare, allergic reactions may occur. Immediately seek emergency veterinarian attention if your pet experiences such a reaction (including swelling of the face, tongue, or lips, hives, or difficulty breathing).

Other severe reactions may occur with or without warning. The most frequently-experienced insulin-related reaction is hypoglycemia (low blood sugar), which may cause the following symptoms:

  • Coma
  • Seizures
  • Staggering gait (incoordination)
  • Lethargy

Immediately reach out to your veterinarian if your pet exhibits signs of a side effect or medical problem. Speak with your veterinarian if your pet seems unusually bothered by a side effect.

What special precautions are there?

Stabilization with short-acting insulin and supportive therapy should be offered to animals who present with:

  • Anorexia
  • Vomiting
  • Lethargy
  • Ketoacidosis

All patients undergoing insulin treatment should be monitored carefully for hyperglycemia and hypoglycemia. This is fundamental in preventing complications and in attaining and maintaining adequate glycemic control.

Incorrect dosing will occur if any syringe is used other than Intervet U-40 Insulin Syringes.

Vetsulin® should only be administered subcutaneously to cats and dogs.

What to do if overdose?

  • Immediately contact your veterinarian or closest in case of overdose
  • rogestogens, certain endocrinopathies, and glucocorticoids can have an antagonistic effect on insulin activity
  • Overdose can result in profound hypoglycemia and death

How can I store Vetsulin?

Store in an upright position under refrigeration at 2° to 8° C (36° to 46° F). Do not freeze. Protect from light.

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